CyTOF analysis of parental and palmitic acid adapted breast cancer cells
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http://flowrepository.org/id/FR-FCM-Z2TK
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资源简介：
Investigate the the cellular phenotypes enriched in breast cancer cells subjected to long-term exposure to palmitic acid (PA).
Conclusion:
Long-term adaptation to PA induced a consistent cellular dedifferentiation towards a cancer stem-cell like phenotype in MDA-MB-231 and HCC1806 cells.
Notes:
Preprint on BioRxiv: C/EBPB-dependent Adaptation to Palmitic Acid Promotes Stemness in Hormone Receptor Negative Breast Cancer https://www.biorxiv.org/content/10.1101/2020.08.11.244509v1 Panel staining was optimised and validated on both MDA-MB-231 and HCC1806 parental and PA-adapted cell line cells. Data are representative of three replicates (ABC) for each condition. Palladium barcoding and EQ normalization beads were used to ensure consistent and comparable signal.
创建时间：
2020-09-01
