Figures and Supplementary Data

Supplementary Table 1: Datasets and software used in this study Supplementary Table 2: List of acne-associated SNPs and SNPs of comorbid diseases used in this study Supplementary Table 3: List of terms used in literature search for identifying comorbid diseases Supplementary Table 4: CoDeS3D output of acne-associated eQTLs and eQTLS associated with comorbid diseases for sun exposed skin Supplementary Table 5: CoDeS3D output of acne-associated eQTLs and eQTLS associated with comorbid diseases for unexposed skin Supplementary Table 6: Comorbid diseases that overlapped the Acne-PPIN (Protein-protein interaction network) significantly for sun exposed and unexposed skin Supplementary Table 7: Biological pathways obtained from g:profiler for sun exposed and unexposed skin Supplementary Table 8: Intersecting genes divided into respective levels for each biological pathway in sun exposed and unexposed skin补充表1：本研究使用的数据集与软件 补充表2：本研究使用的痤疮相关单核苷酸多态性（Single Nucleotide Polymorphism, SNP）及合并症相关单核苷酸多态性列表 补充表3：本研究用于检索识别合并症的文献检索词列表 补充表4：阳光暴露皮肤中痤疮相关表达数量性状位点（expression Quantitative Trait Locus, eQTL）及合并症相关表达数量性状位点的CoDeS3D分析输出结果 补充表5：非阳光暴露皮肤中痤疮相关表达数量性状位点及合并症相关表达数量性状位点的CoDeS3D分析输出结果 补充表6：在阳光暴露与非阳光暴露皮肤中，与痤疮蛋白质相互作用网络（Protein-protein interaction network, PPIN）存在显著重叠的合并症 补充表7：通过g:profiler工具获取的阳光暴露与非阳光暴露皮肤相关生物学通路 补充表8：在阳光暴露与非阳光暴露皮肤中，按各自层级划分至各生物学通路的交集基因