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TP53 knock-down in cultured, starved human adipocytes

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NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE248893
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The goal of this cell culture experiment was to validate in vivo data showing adipocyte p53-dependent changes of the immune cell landscape of visceral adipose tissue in obese mice that are interemittently fasted. Therefore, human SGBS preadipocytes were differentiated into mature adipocytes before TP53 was knocked down via siRNA transfection. twentyfour hours before harvest, the cells were switched to starvation medium (HBSS+HEPES). Control cells were transfected with non-targeting siRNA and also starved. Each group contains triplicate measurements.
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2024-03-01
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