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Next generation sequencing of chicken otocyst with pharmacologicaly induced loss-of-Wnt signalling

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干细胞与再生医学数据中心2022-02-20 更新2024-03-06 收录
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http://data.iscr.ac.cn/Article?id=b8ff982d4e90a50f25688f5e88035f4c
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资源简介:
Bulk RNA-sequencing of individual E2.5 chicken otocyst incubated in media enriched with Wnt signalling inhibitor IWR-1 or control condition (DMSO) for 24h. Transcripts abundance was mapped to a chicken reference genome using Kallisto package and differentially expressed genes were identify using Sleuth package (genes with p-value < 0.05 were considered as significant). Biological Function enrichment analysis (Toppgene online tool) showed that many of these genes were associated with neurogenesis.
提供机构:
UCL Ear Institute
创建时间:
2022-02-20
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