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Extracellular vesicle-associated IGF2BP3 in Ewing Sarcoma cell lines

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NIAID Data Ecosystem2026-03-14 收录
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In this study, we used patient-derived EWS cell lines and IGF2BP3 knock-down/knock-out experimental models to demonstrate that the oncogenic RNA-binding protein IGF2BP3 is secreted by Ewing sarcoma (EWS) cells via extracellular vesicles (EVs)and it contributes to EWS phenotypic heterogeneity.

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2023-03-08
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