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Metal-Free Aminothiation of Alkynes: Three-Component Tandem Annulation toward Indolizine Thiones from 2‑Alkylpyridines, Ynals, and Elemental Sulfur

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NIAID Data Ecosystem2026-03-11 收录
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A metal-free three-component annulation reaction for the synthesis of indolizine thiones via tandem C–C/C–N/C–S bond formation was developed. Various 2-alkylpyridines with aromatic ynals and elemental sulfur proceeded smoothly under catalyst-free conditions, and the desired products were obtained in moderate to excellent yields.

创建时间:
2019-09-23
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