Gene expression profile at single cell level of glial cells from mouse nodose ganglia at postnatal day 4.

The nodose ganglia contain sensory neurons that play key roles in homeostatic behaviors and are supported by nodose glial cells. We used single cell RNA sequencing (scRNA-seq) to interrogate the molecular diversity of nodose glial cells shortly after birth. Nodose glial cells from Phox2bCre;Ai14 mice were isolated by fluorescence activated cell sorting (FACS) according to the presence of cytoplasmic tdTomato at P4 and analyzed using scRNA-seq (CEL-Seq2).