MeRIP-seq used for validation of functional variants in reporter array

NIAID Data Ecosystem2026-03-13 收录

m6A功能变异验证

RNA甲基化功能

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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA794937 数据链接链接失效反馈

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we developed a reporter experiment to validate the finding of ASm6A functional variants in HEK293T cells

创建时间：

2022-01-06

RNA expression in NSUN6 knockout cells. RNA expression in NSUN6 knockout cells

RNA甲基化功能

表观转录组学

mRNA m5C, which has recently been implicated in the regulation of mRNA mobility, metabolism, and translation, plays important regulatory roles in various biological events. Two types of m5C sites are

NIAID Data Ecosystem60

Additional file 4 of m5C methylation of mitochondrial RNA and non-coding RNA by NSUN3 is associated with variant gene expression and asexual blood-stage development in Plasmodium falciparum

疟原虫转录组

RNA甲基化功能

Supplementary Material 4: Table S4. Target genes identified by PfNSUN3 enrichment.

DataCite Commons2025-03-28 更新30

Crystal structure analysis of the methyltransferase domain of bacterial-AvHen1-CN

蛋白质晶体结构解析

RNA甲基化功能

Crystal structure analysis of the methyltransferase domain of bacterial-AvHen1-CN Descriptor: Hen1 Authors: Huang, R.H, Chan, C.M, Zhou, C, Brunzelle, J.S. Deposit date: 2009-09-18 Release date: 2009-

Protein Data Bank Japan2024-02-21 更新20

Mettl14 is required for mouse postimplantation development by facilitating epiblast maturation. Mettl14 is required for mouse postimplantation development by facilitating epiblast maturation

发育表观遗传调控

RNA甲基化功能

N6-methyladenosine (m6A) is the most prevalent and reversible internal modification of mammalian messenger and noncoding RNAs mediated by specificm6A writer, reader, and eraser proteins. As an m6A wri

NIAID Data Ecosystem40

Effect of depletion of METTL3 on gene expression of A549 cells. Effect of depletion of METTL3 on gene expression of A549 cells

癌症分子机制

RNA甲基化功能

To investigate the function of METTL3 in lung cancer, we established shMETTL3 A549 cell line. Overall design: Comparative gene expression profiling analysis of RNA-seq data for METTL3 knockdown and co

NIAID Data Ecosystem20

MeRIP-seq used for validation of functional variants in reporter array

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