We performed RNA-seq experiments, one with the WT control and Ga13ΔM/ΔM osteoclast precursors at baseline and after RANKL stimulation. Overall design: Bone marrow macrophages mRNA profiles of WT and m

NIAID Data Ecosystem30

Correlations between constitutive p-STAT5, TPO induced p-STAT5, and IL6 induced p-STAT3 MFI values and disease parameters tested in circulating CD34 + cells of CALR + patients with PMF.

原发性骨髓纤维化

STAT信号通路

Correlations between constitutive p-STAT5, TPO induced p-STAT5, and IL6 induced p-STAT3 MFI values and disease parameters tested in circulating CD34+ cells of CALR+ patients with PMF.

NIAID Data Ecosystem30

IL-4/STAT6 signaling in eosinophils is required for larval growth.

寄生虫免疫学

STAT信号通路

(A) Body size (area) of larvae, 17dpi. ΔdblGATA mice received PBS or 5 × 106 eosinophils every 48 h between 5 and 9 dpi or 11 and 15 dpi (oral infection). (B)–(C), ΔdblGATA mice received PBS or 5 × 10

NIAID Data Ecosystem40

Growth Factor and Th2 Cytokine Signaling Pathways Converge at STAT6 to Promote Arginase Expression in Progressive Experimental Visceral Leishmaniasis

内脏利什曼病风险分析

STAT信号通路

Host arginase 1 (arg1) expression is a significant contributor to the pathogenesis of progressive visceral leishmaniasis (VL), a neglected tropical disease caused by the intracellular protozoan Leishm

NIAID Data Ecosystem30

STAT5 is a key transcription factor IL-3-mediated inhibition of RANKL-induced osteoclastogenesis

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