Development of 2-imino-2,3,5,6,7,8-hexahydropyrido[4,3-d]pyrimidin-4(1H)-one derivatives as human caseinolytic peptidase P (hClpP) activators
收藏Protein Data Bank Japan2025-04-09 更新2026-06-30 收录
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Development of 2-imino-2,3,5,6,7,8-hexahydropyrido[4,3-d]pyrimidin-4(1H)-one derivatives as human caseinolytic peptidase P (hClpP) activators Descriptor: 5-[(3-fluorophenyl)methyl]-9-[[4-(trifluoromethyl)phenyl]methyl]-1,5,9,11-tetrazatricyclo[8.4.0.0^{2,7}]tetradeca-2(7),10-dien-8-one, ATP-dependent Clp protease proteolytic subunit, mitochondrial, ... Authors: Jiang, J.-X, Ding, H, Chen, M.-R, Lu, M.-L, Sun, H.-Y, Xiao, Y.-B. Deposit date: 2023-10-22 Release date: 2024-10-23 Last modified: 2025-04-09 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Development of novel imipridone derivatives with potent anti-cancer activities as human caseinolytic peptidase P (hClpP) activators. Bioorg.Chem., 153, 2024
创建时间：
2023-10-22
