BF3·Etherate-Mediated Friedel–Crafts Arylation of 2‑Hydroxy-1,4-benzoxazines: Synthesis of 2‑Aryl-1,4-benzoxazine Derivatives
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BF3·etherate-mediated carbon–carbon bond formation by the Friedel–Crafts arylation of 2-hydroxybenzoxazine derivatives with various electron-rich arenes is reported. The current protocol provides an easy access for the synthesis of a series of densely substituted 2-aryl-1,4-benzoxazine derivatives under mild conditions.
创建时间：
2016-02-18
