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Stereoselective Synthesis of Sialylated Tumor-Associated Glycosylamino Acids

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https://figshare.com/articles/dataset/Stereoselective_Synthesis_of_Sialylated_Tumor_Associated_Glycosylamino_Acids/2352997
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资源简介:
Suitably protected sialyl TN and 2,6-sialyl T tumor-associated carbohydrate antigen-derived amino acids have been prepared stereoselectively using an oxazolidinone-derived sialoside donor. These glycosylamino acids can be employed directly in the solid-phase synthesis of glycopeptides, as demonstrated by the efficient preparation of tumor-associated MUC1 glycopeptide fragments.
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2013-11-15
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