In this experiment we demonstrate the use of an inhibitor of the KDM5 family of histone demethylases, KDM5-C70, on H3K4me3 marks in the multiple myeloma cell line MM1S. KDM5-C70 increases H3K4me3 in
We used an combination of long-read and short-read sequencing data to explore the transcriptome of preimplantation embryo Overall design: We selected 7 stage of early embryo including sperm and oocyte
Implant failure and insufficient placental development are important causes of female infertility, recurrent miscarriage, and other pregnancy-related problems. A better understanding of gene expressio
We report the effects of CDK9 inhibition (AZD4573) on the epigenetic landscape in Diffuse Large B-cell Lymphoma (DLBCL). This study utilized the Assay for Transposase-Accessible Chromatin with high-th
Assigned DOI: https://doi.org/10.5258/SOTON/D1086Dataset supports the thesis 'Proteomic analysis of Wntand epigenetic regulatory protein networks in colorectal cancer' chapter 'Chemical knockdown of D
