D & V Hipp. BrdU+ Cells by Age_Data Assoc. w. PMID37146791

Electroconvulsive seizure, vs. sham procedure, was administered once daily for 10 consecutive days to paired male WT and Egr3-/- mice. Brain tissue was collected and cellular proliferation in the hippocampal formation was analyzed via bromodeoxyuridine (BrdU) immunohistochemistry. Analyses investigated whether number of BrdU+ cell counts were associated with animal age. Complete methods are found in associated Data in Brief article (submitted) and original associated article: Meyers, K.T., et al., Serial electroconvulsive Seizure alters dendritic complexity and promotes cellular proliferation in the mouse dentate gyrus; a role for Egr3. Brain Stimul, 2023. 16(3): p. 889-900. https://doi.org/10.1016/j.brs.2023.04.022 PMID: 37146791将电惊厥发作（Electroconvulsive seizure）与假手术对照，每日一次、连续10天给予成对的雄性野生型（Wild Type, WT）及Egr3基因缺失型（Egr3-/-）小鼠。收集脑组织，通过溴脱氧尿苷（bromodeoxyuridine, BrdU）免疫组织化学法分析海马结构中的细胞增殖情况。本分析旨在探究BrdU阳性细胞计数是否与动物年龄存在关联。完整实验方法详见已投稿的《数据简报》（Data in Brief）关联文章，以及原始研究文献：Meyers KT等撰写的《连续性电惊厥发作改变小鼠齿状回的树突复杂性并促进细胞增殖：Egr3的作用》，发表于《Brain Stimul》2023年，第16卷第3期，第889-900页，DOI: 10.1016/j.brs.2023.04.022，PMID: 37146791。