Crystal Structure of Glutamate Carboxypeptidase II in a complex with urea-based inhibitor

Crystal Structure of Glutamate Carboxypeptidase II in a complex with urea-based inhibitor Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... Authors: Tykvart, J, Pachl, P. Deposit date: 2013-11-02 Release date: 2014-06-18 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (1.63 Å) Cite: Rational design of urea-based glutamate carboxypeptidase II (GCPII) inhibitors as versatile tools for specific drug targeting and delivery. Bioorg.Med.Chem., 22, 2014谷氨酸羧肽酶II（Glutamate Carboxypeptidase II, GCPII）与尿素类抑制剂复合的晶体结构。描述项：2-乙酰胺基-2-脱氧-β-D-吡喃葡萄糖（2-acetamido-2-deoxy-beta-D-glucopyranose）、2-乙酰胺基-2-脱氧-β-D-吡喃葡萄糖-(1-4)-2-乙酰胺基-2-脱氧-β-D-吡喃葡萄糖、钙离子（CALCIUM ION）等。作者：Tykvart, J、Pachl, P。提交日期：2013-11-02，发布日期：2014-06-18，最后修改日期：2024-10-30。实验方法：X射线衍射（X-RAY DIFFRACTION，分辨率1.63埃（Å））。引用文献：《尿素类谷氨酸羧肽酶II（GCPII）抑制剂的理性设计：用于特异性药物靶向与递送的多功能工具》，发表于《Bioorg.Med.Chem.》2014年第22卷。