Fbxl22

ENCODES a protein that exhibits ubiquitin protein ligase activity (ortholog); INVOLVED IN proteasome-mediated ubiquitin-dependent protein catabolic process (ortholog); ASSOCIATED WITH Bloom syndrome (ortholog); colorectal cancer (ortholog); hypertrophic cardiomyopathy (ortholog); FOUND IN SCF ubiquitin ligase complex; Z disc; cytosol (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil

编码一种具有泛素蛋白连接酶活性的蛋白质（同源物）；参与蛋白酶体介导的泛素依赖性蛋白质降解过程（同源物）；与布鲁姆综合征（同源物）、结直肠癌（同源物）、肥厚型心肌病（同源物）相关；存在于SCF泛素连接酶复合物中；Z盘；细胞质（同源物）；与2,3,7,8-四氯二苯并-对二恶英；4,4'-磺酰二苯酚；6-丙基-2-硫基尿嘧啶相互作用。