Nonsense SNPs and prediction of NMD.
收藏Figshare2015-12-02 更新2026-05-11 收录
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aThis prediction is based on that mRNA would be destroyed if a stop codon occurs in the 5�� side of the boundary, which is 50�C55 nucleotides upstream from the 3�� end of the second to last exon. Here, the nonsense SNPs located in the 5�� side of the boundary, which was set at 50 nucleotides upstream from the 3�� end of the second to last exon, were predicted to cause NMD.bThis number includes SNPs in genes consisting of only one exon.cP = 0.0033 by Fisher's exact test.
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2015-12-02



