Additional file 2 of PRV-1b and PRV-3a infection is associated with the same clinical disease in coho salmon (Oncorhynchus kisutch) farmed in Chile: unraveling the pathogenesis of the orthoreoviral cardiomyopathy and hemolytic jaundice (OCHJ)

Additional file 2. Histoscore Liver (hsLiver). Histopathological criteria and semi-quantitative weighting used to define histoscore in the liver (hsLiver). Abbreviations: NHC: no histological changes; NIC: no inflammation changes; HCV: hepatocellular cytoplasm vacuoles; TS: tissue surface; NII: necrosis or inflamatory infiltrate; MMC: melanomacrophage cells; HV: hepatocellular vacuolization; NCR: nucleus:cytoplasm ratio; HPZ: hepatic portal zone. Interpretation: hsLiver ≤ 0.9 means a mild liver damage; hsLiver > 0.9 but ≤ 1.8, means a moderate damage; and hsLiver > 1.8 means a severe damage.