Physical properties of pure detergents.

aMonomer volumes were calculated from published specific densities, using the Tanford formula (Vtail = N*(24.7+26.9nc)) for alkyl chain volumes to adjust for different chain lengths.bThe detergent electron density values were computed by summing the number of electrons from the chemical composition and dividing by the molecular volume.cMeasurements performed by Anatrace (Affymetrix, Inc.). All cmcs are reported for conditions of detergent in H2O, except for the cmc of OM which is reported in 20 mM HEPES, pH 7.5 with 100 mM NaCl. Aggregation numbers from ref. [24] are reported in the same buffer used in this study.dA measured value was not found in the literature; although many studies report this aggregation number. However, an estimate can be made from the PDC molecular weight reported by Tian et al. of ∼60 kD [47] (detergent contribution of 44 kD), which yields an aggregation number of ∼90.