We evaluated the in vitro drug–drug interaction (DDI) potential of enerisant (TS-091), a histamine H 3 receptor antagonist/inverse agonist, mediated by cytochrome P450 (CYP) and trans

Taylor & Francis Group2021-07-20 更新50

Classification of Inhibitors of Hepatic Organic Anion Transporting Polypeptides (OATPs): Influence of Protein Expression on Drug–Drug Interactions

药物相互作用预测

转运蛋白抑制剂

The hepatic organic anion transporting polypeptides (OATPs) influence the pharmacokinetics of several drug classes and are involved in many clinical drug–drug interactions. Predicting potential intera

NIAID Data Ecosystem40

The inhibition of OAT1, OAT3, OCT2, OATP1B1, OATP1B3, MATE1 and MATE-2K mediated transport by R- VK4-116.

转运蛋白抑制剂

药物相互作用评估

The inhibition of OAT1, OAT3, OCT2, OATP1B1, OATP1B3, MATE1 and MATE-2K mediated transport by R-VK4-116.

NIAID Data Ecosystem10