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Targeting double-strand break indel byproducts with secondary guide RNAs improves Cas9 HDR-mediated genome editing efficiencies

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NIAID Data Ecosystem2026-04-30 收录
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We report a general strategy (the double tap method) to improve HDR-mediated precision genome editing efficiencies that takes advantage of the reproducible nature of indel sequences.

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2022-03-28
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