Phenotypic proportions (α) and estimated risk allele frequencies (q) in FH−, FH+ and unobserved T2DM-affected family members under a dominant model of inheritance of Adiposity.

Presented as median (95% CI).acalculated from q FH− and qFH+ assuming that the FH− group represents the pool of spouses in the parental generation.bFraction of individuals under the higher Adiposity mode.ccalculated assuming a dominant bi-allelic model of inheritance in Hardy-Weinberg equilibrium.