Additional file 6 of Decreased complement 4 and interleukin-10 as biomarkers in aqueous humour for non-exudative age-related macular degeneration: a case control study

Additional file 6. Assessment of potential bias from age and AMD status in biomarker analyses. Simple regression analysis was performed with AMD status as the predictor for biomarker levels of IL-10, C4, and FI, evaluating R², F-statistic, and P values. Age was then added as a second predictor in a multiple regression to assess model improvement. The same analysis was conducted to evaluate the potential bias of AMD status on the correlation between age and biomarker levels of MMP-1 and CCL20. No significant improvement was observed in either case, indicating that age and AMD status did not influence the respective analyses. * P < .050 represents significance.