Aging is a progressive process that results in the accumulation of intra- and extracellular alterations that in turn contribute to a reduction in health. Age-related changes in DNA methylation have be
While, transcriptional and epigenetic changes associated senescence processes are well studied, the 3D chromatin changes associated with it remains elusive. In this study, we have generated genome wid
DNA methylation levels in whole blood measured over a ten years follow up in an elderly birth cohort of 86 samples Overall design: For each sample, whole blood was drawn in year 1997 and in year 2007
aPhenotypes are listed as follows: Telomere length, systolic blood pressure (SBP), diastolic blood pressure (DBP), Lung function (FVC), grip strength, bone mineral density (BMD), serum levels of DHEAS
