PTEN loss in the fallopian tube induces hyperplasia and ovarian tumor formation

The goals of this study are to compare mouse oviductal transcriptome profiling (RNA-seq) of PTEN-depleted cells by shRNA versus a scr shRNA control expressing PTEN. Overall design: mRNA profiles of PTEN-deficient and control scramble Mouse oviductal cells were generated by deep sequencing, in triplicate, using Illumina HiSeq2500.