Genotypic and allelic frequencies of <i>GRM3</i> polymorphisms in the controls and patients with different diseases.

aThe five P-values for each SNP from top to bottom in one column were calculated by 2×3 and 2×2 chi-squared tests orderly based on codominant, dominant for the rare allele, heterosis and recessive for the rare allele, and allelic models of inheritance. – means that the result could not be obtained by chi-squared test as the given genotype frequency is rare. bOR and 95% CI were calculated by logistic regression analysis with adjustment for demographic factors, including age, gender, education level, unemployment, and life history with family. Statistically significant results with an FPRP value <0.2 are marked in bold. cThe frequency of the homozygote of the minor allele is very rare, and this allele was merged with the heterozygote for a 2×2 chi-squared test. Sz.: schizophrenia, H.D.: heroin dependence, Dep.: depression.