Tests for SNP independence in the interactions observed in the case and control groups.

Each row represents one gene-gene interaction listed in Table 1. Chi-square tests of 3 by 3 contingency tables were used to determine whether two SNPs were dependent in the case group or in the control group. For each test, 10,000 Monte Carlo simulations were used to obtain the p-value; each test was repeated 3 times for both the case group and the control group. The tests were performed with the R statistical software (http://www.r-project.org/).