Exploration of Pipecolate Sulfonamides as Binders of the FK506-Binding Proteins 51 and 52: Complex of FKBP51 with 2-(3-((R)-1-((S)-1-(3,5-dichlorophenylsulfonyl)piperidine-2-carbonyloxy)-3-(3,4-dimethoxy -phenyl)propyl)phenoxy)acetic acid
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Exploration of Pipecolate Sulfonamides as Binders of the FK506-Binding Proteins 51 and 52: Complex of FKBP51 with 2-(3-((R)-1-((S)-1-(3,5-dichlorophenylsulfonyl)piperidine-2-carbonyloxy)-3-(3,4-dimethoxy -phenyl)propyl)phenoxy)acetic acid Descriptor: Peptidyl-prolyl cis-trans isomerase FKBP5, {3-[(1S)-1-[({(2S)-1-[(3,5-dichlorophenyl)sulfonyl]piperidin-2-yl}carbonyl)oxy]-3-(3,4-dimethoxyphenyl)propyl]phenoxy}acetic acid Authors: Gopalakrishnan, R, Kozany, C, Wang, Y, Hoogeland, B, Bracher, A, Hausch, F, Schneider, S. Deposit date: 2012-02-17 Release date: 2012-04-18 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1 Å) Cite: Exploration of Pipecolate Sulfonamides as Binders of the FK506-Binding Proteins 51 and 52. J.Med.Chem., 55, 2012
哌啶甲酸磺酰胺类化合物作为FK506结合蛋白(FK506-Binding Proteins)51和52的配体的探索:FKBP51与2-(3-((R)-1-((S)-1-(3,5-二氯苯基磺酰基)哌啶-2-羰氧基)-3-(3,4-二甲氧基苯基)丙基)苯氧基)乙酸的复合物
描述物:肽基脯氨酰顺反异构酶FKBP5,{3-[(1S)-1-[({(2S)-1-[(3,5-二氯苯基)磺酰基]哌啶-2-基}羰基)氧基]-3-(3,4-二甲氧基苯基)丙基]苯氧基}乙酸
作者:Gopalakrishnan, R、Kozany, C、Wang, Y、Hoogeland, B、Bracher, A、Hausch, F、Schneider, S
提交日期:2012年2月17日
发布日期:2012年4月18日
最后修改日期:2023年9月13日
检测方法:X射线衍射(1埃)
引用文献:《哌啶甲酸磺酰胺类化合物作为FK506结合蛋白51和52的配体的探索》,J.Med.Chem., 55, 2012
创建时间:
2012-02-17



