Epigenetic Mechanisms Regulating the Transcription of BBB Genes: Role of Wnt/β-catenin signaling
收藏NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE214923
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资源简介：
To identify in CNS endothelial cell (EC) the gene cohorts that participate in blood brain barrier (BBB) formation versus maintenance. We investigated mechanisms behind the reduced Wnt/β-catenin signaling observed in adult CNS ECs We also investigated whether the adult endothelial cells can re express the EC gene cohorts required for the BBB formation. Comparative gene expression profiling analysis of RNA-seq data for E-13.5 cortical ECs vs Adult Cortical ECs, vs Wnt3a (200nM) treated Adult cortical Ecs, Adult cortical ECs versus MS-275 (10uM) treated cortical ECs.
创建时间：
2025-01-02
