Overall accuracy of denoised pyrosequences and 3% OTUs retained by APDP and three alternative denoising approaches using six artificial community datasets.

Bold numbers indicate best result in the column. The number of false positives (FP) and false negatives (FN) is shown for cases where miscalled and near-match OTUs are considered to be incorrect (TP only) or correct (TP+NM and TP+MC+NM). In addition, the results are shown for each method after excluding OTUs with fewer reads than the minimum detection threshold of APDP (cutoff).