Highly upregulated mRNAs show mostly negative selection (site avoidance) for miRNA binding sites.

List of miRNAs with negative selection (avoidance of binding sites) among 40 highly eIF4E upregulated mRNAs (fold change greater 4.0) and 1200 nonregulated mRNAs (fold change between 1.05 and 1.0/1.05). upreg+: number of upregulated mRNAs that show positive selection with respect to the specified miRNA, upreg−: number of upregulated mRNAs with negative selection, nonreg+: number of nonregulated mRNAs with positive selection of miRNA-target binding sites; nonreg−: number of nonregulated mRNAs with negative selection. P-values are computed according using a Fisher exact test, all entries with a p-value smaller than 0.02 are listed. Ratio: (upreg+/(upreg++upreg−))/(nonreg+/(nonreg++nonreg−)).