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BRI2-mediated regulation of TREM2 processing in microglia and its potential implications for Alzheimer's disease and related dementias

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We used single cell RNA sequencing (scRNA-seq) to analyze the expression changes in microglia association of genomic changes of Bri2 or/and Trem2 microglia were isolated from adult mice brains using CD11b magnetic beads and performed with scRNAseq analysis

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