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Asymmetric robustness in the feedback control of the retinoic acid network response to environmental disturbances

NIAID Data Ecosystem2026-03-13 收录

视黄酸信号通路

生物系统鲁棒性

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE154408 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2021-11-10

基因表达谱分析

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The metabolism of ROL to the biogenesis of ATRA occurs in the cytoplasms of hepatocytes, which in turn translocates into nucleus upon binding to Cellular Retinoic Acid Binding Proteins, CRABP1 or CRAB

NIAID Data Ecosystem100

Text S1 - Evolution of Robustness to Noise and Mutation in Gene Expression Dynamics

基因表达调控

生物系统鲁棒性

Derivation of General Relationship on Fluctuations. Mathematical derivation on general relationships on phenotypic variances is presented. (0.05 MB PDF)

NIAID Data Ecosystem40

Quantifying Global Tolerance of Biochemical Systems: Design Implications for Moiety-Transfer Cycles

生物系统鲁棒性

部分转移循环建模

Robustness of organisms is widely observed although difficult to precisely characterize. Performance can remain nearly constant within some neighborhood of the normal operating regime, leading to home

NIAID Data Ecosystem30

MYT1 attenuates neuroblastoma cell differentiation by inhibiting retinoic acid signaling pathway

神经母细胞瘤分子机制

视黄酸信号通路

This study first reveals that MYT1 is a potential oncogene in neuroblastoma, which is significantly correlated with poor prognosis and represses cellular differentiation via interrupting retinoic acid

NIAID Data Ecosystem70

Antibodies used for western blot analysis.

视黄酸信号通路

角膜缘上皮细胞

Purpose In the present study, we evaluate gene and protein expression levels in an in vitro siRNA-mediated PAX6 knockdown limbal epithelial cell (LEC) model after RA treatment. This study aims to inve

NIAID Data Ecosystem30

Asymmetric robustness in the feedback control of the retinoic acid network response to environmental disturbances

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