首页/数据集/The splicing factor RBM4 controls apoptosis, proliferation, and migration to suppress tumor progression. Homo sapiens

The splicing factor RBM4 controls apoptosis, proliferation, and migration to suppress tumor progression. Homo sapiens

NIAID Data Ecosystem2026-03-08 收录

肿瘤抑制机制

RNA剪接调控

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA252956 数据链接链接失效反馈

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资源简介：

Gene expression and splicing switches upon RBM4 overexpression Overall design: 2 Samples

应用场景：

创建时间：

2014-06-17

肿瘤抑制机制

铁死亡调控

The tumor suppressor protein p53 suppresses cancer by regulating processes such as apoptosis, cell cycle arrest, senescence, and ferroptosis. Whereas numerous p53 target genes have been identified, o

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The zinc finger domains in U2AF26 and U2AF35 have diverse functionalities including a role in controlling translation

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翻译控制

Recent work has associated point mutations in both zinc fingers (ZnF) of the spliceosome component U2AF35 with malignant transformation. However, surprisingly little is known about the functionality o

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The impact of Prp18p on splicing fidelity and efficiency in budding yeast

剪接保真度

RNA剪接调控

Fidelity of 3´-splice site (3´SS) selection by the spliceosome is critical for proper gene expression but is a daunting task considering the low complexity of the 3´SS consensus YAG. Here we show that

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Glucose dissociates DDX21 dimers to regulate mRNA processing and promote epidermal differentiation (RNA-Seq II)

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Glucose is an important cellular energy source, however, glucose's function as a second messenger remains relatively unexplored. Here, we find that glucose binds directly to DDX21 to regulate its func

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The splicing factor RBM4 controls apoptosis, proliferation, and migration to suppress tumor progression. Homo sapiens

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