Derived data and figure source data for patient-level progenitor-like and inflammatory-chemokine programs in double-negative prostate cancer
收藏资源简介:
This dataset accompanies the manuscript “Patient-level progenitor-like and inflammatory-chemokine programs in double-negative prostate cancer with modest AR-low spatial colocalization.” The archive contains derived results from processed public transcriptomic datasets GSE126078, GSE278936 and GSE150368. It includes frozen gene-module definitions and scoring rules, dataset-level signature coverage, patient-level DNPC-versus-ARPC results, patient-section-level spatial endpoints, paired pre- and post-androgen-deprivation tissue results, formal and descriptive statistical summaries, integrated evidence and claim-boundary tables, source data for Figures 1–4 and Supplementary Figures S1–S3, selected derived Visium spot-score files for GSM8557994 and GSM8558018, and Supplementary Tables S1–S11. The primary inference units are patients for GSE126078, patient sections for GSE278936 and patient pairs for GSE150368. No pooled lesion-level or pooled Visium-spot observations are treated as independent patient observations. The archive contains derived data only. It does not redistribute raw sequencing reads, controlled-access data, identifiable patient information or complete third-party GEO expression matrices. Bulk-tissue and Visium analyses do not establish same-cell coexpression, malignant-cell origin, treatment causality, tumor-specific induction or a resistance mechanism.



