N-acetylornithine aminotransferase from S. typhimurium complexed with L-canaline
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N-acetylornithine aminotransferase from S. typhimurium complexed with L-canaline Descriptor: (2S)-2-azanyl-4-[(E)-[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methylideneamino]oxy-butanoic acid, 1,2-ETHANEDIOL, ACETATE ION, ... Authors: Bisht, S, Bharath, S.R, Murthy, M.R.N. Deposit date: 2013-02-27 Release date: 2014-03-26 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.48 Å) Cite: Conformational transitions, ligand specificity and catalysis in N-acetylornithine aminotransferase: Implications on drug designing and rational enzyme engineering in omega aminotransferases. To be Published
来自鼠伤寒沙门氏菌(S. typhimurium)的N-乙酰鸟氨酸氨基转移酶(N-acetylornithine aminotransferase)与L-刀豆氨酸(L-canaline)的复合晶体。 复合物组分描述:(2S)-2-氨基-4-[(E)-[2-甲基-3-羟基-5-(膦酰氧基甲基)吡啶-4-基]亚甲氨基]氧基丁酸、1,2-乙二醇、乙酸根离子等。 作者:比什特(Bisht, S)、巴拉特(Bharath, S.R)、穆尔蒂(Murthy, M.R.N.) 提交日期:2013-02-27 发布日期:2014-03-26 最后更新日期:2023-11-08 测试方法:X射线衍射(分辨率1.48埃) 引用文献:《N-乙酰鸟氨酸氨基转移酶的构象转变、配体特异性与催化作用:对ω-氨基转移酶的药物设计与理性酶工程的启示》,待发表



