This study provides the first systematic CRIPSR screening of tumour suppressor genes (TSGs) in vivo and identifies bona fide TSGs especially for epigenetic regulators contributing to lung tumour progr
A cellular spatial transcriptomic atlas of non-small cell lung cancer (NSCLC) is presented with data from 527 patient cores profiled at the cellular level with the Bruker CosMx whole transcriptome ima
IntroductionThe composition and remodelling of the extracellular matrix (ECM) are important factors in the development and progression of cancers, and the ECM is implicated in promoting tumour growth