System-wide analysis of SUMOylation dynamics in response to replication stress reveals novel SUMO target proteins and acceptor lysines relevant for genome stability.

Data from ProteomeXchange, PXD ID: PXD001736. File: 20140408_QE_UP_U2OS1222_2h_04a.mzml. Published as part of . From the Abstract: {{i}} To address this, we have purified and identified SUMO-2 target proteins regulated by replication stress in human cells. The developed methodology enabled single step purification of His10-SUMO-2 conjugates under denaturing conditions with high yield and high purity ... {{/i}}