Data for "Hydration-Mediated G-Protein-Coupled Receptor Activation"

This data repository includes the follwing data. <strong>Tabulated data indicating effects on ln </strong><em><strong>K </strong></em><strong>by the small osmolytes PEG 200, PEG 300, PEG 400, PEG 600 and Sucrose.</strong> Listed are the weight percentages of each osmolyte in the sample solution, the calculated osmotic pressures. <strong>Tabulated</strong> <strong>data</strong> <strong>indicating</strong> <strong>effects</strong> <strong>on</strong> <strong>ln</strong> <em><strong>K</strong></em> <strong>by</strong> <strong>the</strong> <strong>large</strong> <strong>osmolytes</strong> <strong>PEG</strong> <strong>1000,</strong> <strong>PEG</strong> <strong>1500, PEG 2000, PEG 3000, PEG 4000</strong> <strong>and</strong> <strong>PEG</strong> <strong>6000.</strong> Listed are the weight percentages of each osmolyte in the sample, the calculated osmotic pressures. <strong>The numbers of hydrating water molecules and curvature term</strong>, reflected by a change in virial coefficient Δ<em>C </em>or change in compressibility Δ<em>κ </em>for a standard-state MI-MII transition were calculated for the response of rhodopsin to various molecular weight osmolytes. <strong>Tabulated pH</strong> <strong>titration</strong> <strong>data,</strong> where MII fractions (<em>θ</em>) are taken from the fitting of basis spectra to the experimental spectra. <strong>Tabulated p</strong><em><strong>K</strong></em>_{<strong>A</strong>} <strong>values and alkaline endpoints. </strong> <i>For inquiries regarding the contents of this dataset, please contact the Corresponding Author listed in the README.txt file. Administrative inquiries (e.g., removal requests, trouble downloading, etc.) can be directed to [e-mail]</i>