Ternary structure of 14-3-3s, BRAF phosphopeptide (pS365) and compound 22 (1083853).
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Ternary structure of 14-3-3s, BRAF phosphopeptide (pS365) and compound 22 (1083853). Descriptor: 14-3-3 protein sigma, BRAF peptide pS365, CHLORIDE ION, ... Authors: Konstantinidou, M, Vickery, H, Pennings, M.A.M, Virta, J, Visser, E.J, Oetelaar, M.C.M, Overmans, M, Neitz, J, Ottmann, C, Brunsveld, L, Arkin, M.R. Deposit date: 2023-10-10 Release date: 2025-04-23 Last modified: 2026-03-04 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Modulation of the 14-3-3 sigma /C-RAF "Auto"inhibited Complex by Molecular Glues. J.Am.Chem.Soc., 148, 2026
14-3-3蛋白(14-3-3)、BRAF磷酸肽(pS365)与化合物22(编号1083853)的三元复合物结构。结构描述:14-3-3σ蛋白、BRAF pS365肽段、氯离子…… 作者:Konstantinidou M、Vickery H、Pennings M.A.M、Virta J、Visser E.J、Oetelaar M.C.M、Overmans M、Neitz J、Ottmann C、Brunsveld L、Arkin M.R 提交日期:2023-10-10 发布日期:2025-04-23 最后更新日期:2026-03-04 检测方法:X射线衍射(X-RAY DIFFRACTION,分辨率1.8 Å) 引用文献:《通过分子胶调控14-3-3σ / C-RAF"Auto"抑制复合物》,《美国化学会志》(J.Am.Chem.Soc.),第148卷,2026年



