ChIP-Seq for Pbx1 in the mouse E12.5 ventral midbrain

NIAID Data Ecosystem2026-03-11 收录

多巴胺能神经元发育

帕金森病转录调控

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE82098 数据链接链接失效反馈

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资源简介：

Investigations into the roles for Pbx1 and its transcriptional network in dopaminergic neuron development and Parkinson's Disease One sample each for Pbx1, IgG, and input

创建时间：

2019-05-15

Foggy mutant: brain (Guo-1R01NS042626-01A2). Danio rerio

多巴胺能神经元发育

斑马鱼疾病模型

The foggy mutant zebrafish show severe deficits in dopaminergic neurons, thus is an important tool to understanding the development of these neurons, which undergo degeneration in Parkinson's disease.

NIAID Data Ecosystem70

Identification of ASCL1 as a determinant for human iPSC-derived dopaminergic neurons

神经细胞分化

多巴胺能神经元发育

To better understand how human pluripotent stem cells (hPSCs) differentiate from progenitor cells into distinct neuronal states, we performed 10x single cell RNA sequencing on in vitro directed differ

NIAID Data Ecosystem40

Integrative genome-wide analysis of dopaminergic neuron-specific PARIS expression dissects recognition of multiple PPAR-? associated gene regulation (ChIP-Seq).

帕金森病转录调控

ChIP-seq基因靶点分析

PURPOSE: The transcriptional repressor PARIS (ZNF746) was initially identified as a pathogenic co-substrate of PINK1 and parkin that leads to Parkinson's disease (PD) by disrupting mitochondrial bioge

NIAID Data Ecosystem40

FJ001: Retinoic acid-dependent and -independent gene-regulatory pathways of Pitx3 in meso-diencephalic dopaminergic neurons. Mus musculus

多巴胺能神经元发育

Pitx3基因调控

Development of meso-diencephalic dopamine (mdDA) neurons requires the combined actions of the orphan nuclear receptor Nurr1 and the paired-like homeobox transcription factor Pitx3. Whereas all mdDA ne

NIAID Data Ecosystem50

Dose-dependent and subset-specific regulation of midbrain dopaminergic neuron differentiation by LEF1-mediated WNT1/b-Catenin signaling. Mus musculus

多巴胺能神经元发育

WNT/β-catenin信号调控

The development of the mesodiencephalic dopaminergic (mdDA) neurons strongly depends on the WNT1/b-catenin signaling pathway. These neurons include the Substantia nigra pars compacta (SNc) subset that

NIAID Data Ecosystem40

ChIP-Seq for Pbx1 in the mouse E12.5 ventral midbrain

资源简介：

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