Changes in pregnant human myometrial contractile parameters in response to NaHS, and GYY4137 incubations with and without oxytocin.

After baseline values were obtained (30 minute period immediately before incubation in experimental solutions,100%), tissues were incubated in either physiological saline (control) or the solutions indicated, for 45 minutes and then the parameters of contraction re-measured, and expressed as the percent of baseline values (i.e. paired data).Values are means ± s.e.m.*represents significant differences in contractility compared to preceding control period.(p‡represents significant reduction in spontaneous contractility when compared to, in the presence of oxytocin (0.5 nM) along with either GYY4137 or NaHS. AUC; area under the curve.