Regulation of nuclear transcription by mitochondrial RNAs [scRNA-seq/snRNA-seq]. Regulation of nuclear transcription by mitochondrial RNAs [scRNA-seq/snRNA-seq]

To understand the SncmtRNA-regulated endothelial gene expression. We performed single cell and single nuclear RNA-seq in endothelial cells with inhibition of SncmtRNA. Overall design: Performing single-cell and single-nuclear RNA-seq in HUVECs upon knockdown of SncmtRNA and treatment with 25 mM high-glucose + 5ng/ml TNFa