Patient characteristics for the groups with Gleason score ≤7 or >7 and differences in HIF1α expression between the groups.

The group with Gleason score ≤7 was comprised of Gleason score 7 was comprised of scores 8 (8), 9 (52) and 10 (2).†There were 17 patients with missing data for tumor stage in the group with Gleason score >7 and 16 of these patients were HIF1α positive.¥There was no significant association with HIF1α expression and Gleason scores when analyzed using Pearson’s Chi-squared test or Fisher’s exact test using two-by-two tables.*Pre-interventional PSA was defined as PSA immediately prior to obtaining the tissue sample.