Reactivity Data

Reactivity profiles for MS2 RNA which has undergone X-ray footprinting in transcript, <i>in virio</i>, post extraction and post reassembly.<br>footprinted samples have been processed using capillary electrophoresis (CE) and the CE traces have been analysed using the BoXFP software package. <br>Each file contains 3 columns; the first details the positions of the datapoints in the MS2 genome; the second column contains the average reactivity values; the third column contains the standard errors on the mean for the reactivity values. <br>The files ending <i>reacs.csv </i>contains the unnormalised reactivity profiles whilst those ending <i>reacsNorm.csv</i> contain the normalised reactivity profiles. The primer used, treatment condition, and X-ray exposure time is also provided in the label of the files. <br>Note that all profiles have been corrected against background samples (0 ms exposed samples). means and standard errors on the mean are taken over 3 replicates excepted for the primer 6 Virion and Reassembled samples which are over two replicates.