Transcription profiling of striatum from 12 weeks-old R6/2 mice and control mice (set 2)

ChEBI2008-06-16 更新2026-07-21 收录

亨廷顿病动物模型

纹状体转录组学

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-9804 数据链接链接失效反馈

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资源简介：

Transcription profiling of striatum from 12 weeks-old R6/2 mice and control mice (set 2)

创建时间：

2008-06-16

Data_Sheet_2_The Effects of Selective Inhibition of Histone Deacetylase 1 and 3 in Huntington’s Disease Mice.xlsx

亨廷顿病动物模型

HDAC抑制剂

Huntington’s disease (HD) is an autosomal dominant neurodegenerative disease characterized by a late clinical onset of psychiatric, cognitive, and motor symptoms. Transcriptional dysregulation is an e

NIAID Data Ecosystem90

Striatal genes regulated by super-enhancers and displaying low paused RNAPII are preferentially down-regulated in Huntington’s disease [RNA-seq]. Mus musculus

亨廷顿病分子机制

纹状体转录组学

Huntington neurodegenerative disease (HD) is associated with extensive down-regulation of neuronal genes. We show preferential down-regulation of super-enhancer-regulated neuronal function genes in th

NIAID Data Ecosystem30

Chronic mitochondrial energy impairment produces selective striatal degeneration and abnormal choreiform movements in primates.

亨廷顿病动物模型

线粒体能量代谢障碍

Although the gene defect responsible for Huntington disease (HD) has recently been identified, the pathogenesis of the disease remains obscure. One potential mechanism is that the gene defect may lead

PubMed Central1995-07-18 更新20

Striatal genes regulated by super-enhancers and displaying low paused RNAPII are preferentially down-regulated in Huntington’s disease [ChIP-seq]

亨廷顿病基因调控

纹状体转录组学

NIAID Data Ecosystem60

Tolerance to cocaine-induced motor effects in rats: transcriptomic regulations in the ventral striatum

可卡因成瘾耐受性

纹状体转录组学

Comparison of gene expression in the dorsal striatum of rats after chronic binge or acute binge cocaine injections or saline treatment

Alliance of Genome Resources20