Multi-parametric MRI of Focused Ultrasound (FUS) ablations in rabbit muscle tissue

This dataset contains MRI data acquired approximately 20 minutes before (Pre-ablation) and 20-40 minutes after (Post-ablation) MR-guided focused ultrasound thermal ablations in the muscle tissue (quadriceps) in four (n=4) New Zealand white rabbits. MR images include MR thermometry acquired with the proton resonance frenquency method, ADC maps (b=0,400), T2-weighted, and pre- and post-contrast enhanced T1-weighted images. All MRI acquisitions were 3D except for the ADC acquisition, which was 2D multi-slice. This dataset also includes a 3D binary segmentation of histological thermal necrosis, as determined by 3D-registered H&E digital pathology. Furthermore, a 3D binary segmentation of the quadricep muscle is included for each subject. All datasets are resampled to a common FOV at 1-mm isotropic resolution. Details of data acquisition can be found in the IEEE Transactions in Biomedical Engineering publication titled 'A non-contrast multi-parametric MRI biomarker for assessment of MR-guided focused ultrasound thermal therapies.'