The gene expression profiling in the brain of cGAS or STING deficiency mice

Mounting evidence indicates that the cGAS-STING pathway represents the major DNA sensing pathway to invoke immune and inflammatory responses in neuroinflammatory disorders. Here, we examinedgene expression profiling in the brain of cGAS and STING deficiency mice Overall design: Total RNA of brain from cGAS or STING knockout mouse after ischemic stroke was isolated and sequenced by deep sequencing using Illumina HiSeq 2500