To gain insights into the role of a repeat-derived piRNA in Aedes aegypti, Aag2 cells were transfected with 500 nM of an antisense oligonucleotide for 48h, or Ae. aegypti Jane embryos were injected wi
To gain insights into the functions of non repeat-derived Piwi-interacting RNAs (piRNAs) in Aedes aegypti we blocked a highly abundant piRNA (propiR1) with antisense oligonucleotides in the somatic ce
As is the case in vertebrates, successful mosquito immune responses depend on a complex and carefully orchestrated network of processes in order to defend the host from a foreign invader and to simult