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The immunodominant LF epitopes, identified in transgenic mouse strains, show relatively broad binding to common HLA-DR alleles.

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NIAID Data Ecosystem2026-03-08 收录
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The relative binding affinity of peptides to HLA-DR molecules were expressed as a relative activity (ratio of the IC50 of the peptide to the IC50 of the reference peptide which binds strongly to the individual HLA II molecule). Peptides with a high relative binding affinity of <10 are indicated in bold. Means were calculated from at least three independent experiments.

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2014-05-01
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